• 专利标题:   Manufacturing photoacoustic ultrasound generator, comprises e.g. forming uncured prepolymer polydimethylsiloxane (PDMS) film on substrate, and spraying solution of light-absorbing nanoparticles onto surface of uncured PDMS film.
  • 专利号:   US2021047486-A1, KR2220412-B1, KR2021019837-A
  • 发明人:   BAAC H W, SANG P G, HEO J M, BAACHYOUNGWON, MIN H J
  • 专利权人:   UNIV SUNGKYUNKWAN RES BUSINESS FOUND, UNIV SUNGKYUNKWAN RES BUSINESS FOUND
  • 国际专利分类:   A61B005/00, B05D007/00, B32B027/08, B32B027/18, B32B027/28, C08J005/18, C08K003/04, C08L083/04, B06B001/02, C09D001/00
  • 专利详细信息:   US2021047486-A1 18 Feb 2021 C08J-005/18 202120 English
  • 申请详细信息:   US2021047486-A1 US991171 12 Aug 2020
  • 优先权号:   KR098955

▎ 摘  要

NOVELTY - Manufacturing a photoacoustic ultrasound generator, comprises: forming an uncured prepolymer polydimethylsiloxane (PDMS) film on a substrate; spraying a solution of light-absorbing nanoparticles onto a surface of the uncured PDMS film, and then permeating and diffusing the light-absorbing nanoparticles into the uncured PDMS film; and curing the uncured PDMS film containing the light-absorbing nanoparticles distributed there to form a composite film of nanoparticles and PDMS. USE - The method is useful for manufacturing a photoacoustic ultrasound generator (claimed) with high laser-induced damage threshold. ADVANTAGE - The method: alleviates an exceedingly high thermal load, which can cause film damage or ablation; results in the increase of laser-induced damage threshold and the maximum-available ultrasound output from the photoacoustic ultrasound generator; is capable of generating high-amplitude and high-frequency ultrasound using optical energy and an ultrasound generator; provides photoacoustic generator, which has high laser-induced damage threshold and high energy-conversion efficiency at the same time enables to generate the high-amplitude ultrasound ultimately, and enables to receive and absorb a higher input laser energy without damage or film ablation; requires high spatial density of light-absorbing nanoparticles and mechanical robustness; utilizes PDMS composite film that receives a higher laser energy fluence and converts into a thermal energy without damaging the composite film, as compared to the conventional composite films; and offers PDMS coating on top of the composite film fabricated above, which may stably protect the light-absorbing nanoparticles from exposed to an environment out of the PDMS medium. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for: (1) an ultrasound generator comprising (a) a top PDMS layer, and (b) a bottom layer of carbon nanotube (CNT)-dispersed PDMS composite formed on a substrate, where the CNTs are dispersed so that a mean distance between the CNTs is substantially equal to or larger than a thermal diffusion length during the temporal width of an irradiation laser pulse; and (2) a medical device including an ultrasound generator, where the ultrasound generator comprises the components (a)-(b) as per se.