▎ 摘　　要

NOVELTY - A solid-phase extraction column comprises separation column and solid-phase extraction agent filled within the separation column. The solid-phase extraction agent is graphene or modified graphene. The graphene is monolayered graphene or multi-layered graphene. The modified graphene is chosen from e.g. amino graphene, carboxylated graphene, cyano graphene, nitro graphene, boronic acid group-containing graphene, phosphoric acid group-containing graphene, hydroxyl group-containing graphene, mercapto graphene, methylated graphene, allyl graphene and trifluoromethylated graphene. USE - Solid-phase extraction column is used in pre-treatment of chemical sample (claimed). ADVANTAGE - The solid-phase extraction column has high separation efficiency. DETAILED DESCRIPTION - A solid-phase extraction column comprises separation column and solid-phase extraction agent filled within the separation column. The solid-phase extraction agent is graphene or modified graphene. The graphene is monolayered graphene or multi-layered graphene. The modified graphene is chosen from amino graphene, carboxylated graphene, cyano graphene, nitro graphene, boronic acid group-containing graphene, phosphoric acid group-containing graphene, hydroxyl group-containing graphene, mercapto graphene, methylated graphene, allyl graphene, trifluoromethylated graphene, dodecyl graphene, octadecyl graphene, fluorinated graphene, brominated graphene, chlorinated graphene and iodinated graphene. INDEPENDENT CLAIMS are included for the following: (1) preparation of solid-phase extraction column; and (2) pre-treatment of chemical sample, which involves activating solid-phase extraction column, injecting to-be-processed chemical sample and eluting.