• 专利标题:   Preparing antibacterial and anticoagulant nano-copper-fluorinated graphene coated dialysis catheter comprises soaking dialysis catheter in nano-copper-acetone solution prepared by mixing nano-copper particles with acetone solution, swelling treating, and constructing fluorinated graphene coating.
  • 专利号:   CN115944789-A, CN115944789-B
  • 发明人:   LIU C, LIU Z, ZHANG L
  • 专利权人:   UNIV SICHUAN, UNIV SICHUAN WEST CHINA HOSPITAL
  • 国际专利分类:   A61L029/10, A61L029/16, A61L033/02, C25D015/00
  • 专利详细信息:   CN115944789-A 11 Apr 2023 A61L-029/10 202344 Chinese
  • 申请详细信息:   CN115944789-A CN10241482 14 Mar 2023
  • 优先权号:   CN10241482

▎ 摘  要

NOVELTY - Preparing antibacterial and anticoagulant nano-copper-fluorinated graphene coated dialysis catheter comprises (1) mixing nano-copper particles with acetone solution to obtain nano-copper-acetone solution, (2) soaking the dialysis catheter into the nano-copper-acetone solution, and performing swelling treatment to obtain a copper-embedded dialysis catheter, and (3) constructing a fluorinated graphene coating on the surface of the copper-embedded dialysis catheter to obtain final product, where the silane coupling agent used in constructing process of fluorinated graphene coating on the surface of the copper-embedded dialysis catheter is 1H,1H,2H,2H-perfluorooctyltriethoxysilane, 1H,1H,2H,2H-perfluorooctyltriethoxysilane or 1H,1H,2H,2H-perfluorodecyltriethoxysilane. USE - The method is useful for preparing antibacterial and anticoagulant nano-copper-fluorinated graphene coated dialysis catheter. ADVANTAGE - The method: ensures the dialysis catheter has obvious bactericidal effect, which can significantly reduce platelet adhesion, activation and loss of platelets in the blood, and reduce the risk of thrombosis. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for antibacterial and anticoagulant nano-copper-fluorinated graphene coated dialysis catheter prepared by above method.