• 专利标题:   Nanocomposite, useful for delivering camptothecin to tumor cell of human, comprises graphene oxide-grafted polymer loaded with medical active ingredient.
  • 专利号:   KR2014106252-A, KR1476029-B1
  • 发明人:   PARK S Y, THANGAVELU K
  • 专利权人:   UNIV KYUNGPOOK NAT IND ACAD COOP FOUND
  • 国际专利分类:   A61K031/475, A61K047/30, A61K047/48, A61K009/08
  • 专利详细信息:   KR2014106252-A 03 Sep 2014 A61K-047/48 201467 Pages: 17
  • 申请详细信息:   KR2014106252-A KR020567 26 Feb 2013
  • 优先权号:   KR020567

▎ 摘  要

NOVELTY - Nanocomposite comprises graphene oxide-grafted polymer loaded with a medical active ingredient at 37 degrees C, where the medical active ingredient is released at a rate of less than 5% for 48 hours at 37 degrees C at a pH of greater than 7.4 and at a rate of 30% for 48 hours at a pH of less than 7. USE - The nanocomposite is useful for delivering an anti-cancer drug, preferably camptothecin (all claimed), to tumor cell of a target i.e. human. Tests details are described but no results given. ADVANTAGE - The nanocomposite efficiently delivers the drug having excellent solubility and stability to the site of the target in a controlled manner with reduced side effects. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for producing nanocomposite comprising grafting polymer with graphene oxide.