• 专利标题:   Electronic device comprises platinum-based electrode having protective layer thereon comprising graphene in amount effective to reduce platinum corrosion of electrode.
  • 专利号:   US2021228864-A1
  • 发明人:   CHEN Z, PARK H, LEE H
  • 专利权人:   PURDUE RES FOUND
  • 国际专利分类:   A61N001/04, A61N001/36, H01B005/00, H01B013/32, A61N001/05
  • 专利详细信息:   US2021228864-A1 29 Jul 2021 A61N-001/05 202167 English
  • 申请详细信息:   US2021228864-A1 US143491 07 Jan 2021
  • 优先权号:   US958485P, US143491

▎ 摘  要

NOVELTY - Electronic device comprises platinum-based electrode having protective layer thereon comprising graphene in amount effective to reduce platinum corrosion of electrode. USE - Electronic device. ADVANTAGE - The electronic device reduces platinum corrosion and mitochondrial activity, and induces oxidative stress on cells. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following: 1. a method for producing electronic device, which involves: a. chronically implanting neurostimulation device in subject to target subcortical, cortical, spinal, cranial, or peripheral nerve structures, modulate neuronal activity, and provide therapeutic effect for neuropsychiatric disorder; 2. a method for producing electrode of electronic device, which involves: a. providing platinum-based electrode on surface of substrate; b. applying protective layer comprising graphene on electrode; 3. a method for producing electrode for neurostimulation device configured to induce therapeutic neuromodulation of neural circuitry, which involves: a. providing platinum-based electrode on substrate; b. applying protective layer comprising monolayer of graphene on electrode.