• 专利标题:   Polydopamine-modified reduced graphene oxide for use in e.g. photoacoustic ultrasound multimodal imaging, comprises reduced graphene oxide and polydopamine which is physically adsorbed to surface of reduced graphene oxide.
  • 专利号:   CN104399090-A
  • 发明人:   CAI L, HU D, SHENG Z, ZHANG J
  • 专利权人:   SHENZHEN INST ADVANCED TECHNOLOGY
  • 国际专利分类:   A61K041/00, A61K049/00, A61P035/00
  • 专利详细信息:   CN104399090-A 11 Mar 2015 A61K-049/00 201535 Pages: 12 Chinese
  • 申请详细信息:   CN104399090-A CN10637948 12 Nov 2014
  • 优先权号:   CN10637948

▎ 摘  要

NOVELTY - Polydopamine-modified reduced graphene oxide comprises reduced graphene oxide and polydopamine which is physically adsorbed to the surface of reduced graphene oxide. USE - Polydopamine-modified reduced graphene oxide is used in photoacoustic ultrasound multimodal imaging or in preparation of photothermal cancer therapy applications (all claimed). ADVANTAGE - The polydopamine-modified reduced graphene oxide can be mass-produced by a simple and environment-friendly method at low reduction temperature, without using a stabilizer. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for preparation of polydopamine-modified reduced graphene oxide, which involves completely dissolving graphene oxide and dopine hydrochloride in a mass ratio of (1-4):(1-4) in a solvent to obtain a mixed solution, adjusting the pH of mixed solution to 8.5-9, and reacting at 55-65 degrees C for 12-24 hours.