• 专利标题:   New ultra-sensitive and supramolecular graphene oxide intelligent drug carrier used for loading anti-tumor drug.
  • 专利号:   CN105688226-A, CN105688226-B
  • 发明人:   LIU X, WEN H, XUE W, HAO F, HUANG S
  • 专利权人:   UNIV NORTHWEST
  • 国际专利分类:   A61K031/704, A61K047/48, A61P035/00, C08B037/16, A61K047/69
  • 专利详细信息:   CN105688226-A 22 Jun 2016 A61K-047/48 201678 Pages: 17 Chinese
  • 申请详细信息:   CN105688226-A CN10133135 09 Mar 2016
  • 优先权号:   CN10133135

▎ 摘  要

NOVELTY - Ultra-sensitive and supramolecular graphene oxide intelligent drug carrier (I) is new. USE - Ultra-sensitive and supramolecular graphene oxide intelligent drug carrier used for loading anti-tumor drug (claimed). ADVANTAGE - The ultra-sensitive and supramolecular graphene oxide intelligent drug carrier has pi-pi and hydrophobic interactions, and ensures increased loading of hydrophobic drug, and rapid cleavage of disulfide bond in tumor cells to facilitate intelligent drug release function. DETAILED DESCRIPTION - Ultra-sensitive and supramolecular graphene oxide intelligent drug carrier of formula (I) is new. SS=disulfide group; and R=alpha-cyclodextrin, beta-cyclodextrin or gamma-cyclodextrin. An INDEPENDENT CLAIM is included for a method for preparing ultra-sensitive and supramolecular graphene oxide intelligent drug carrier..