• 专利标题:   Preparing antibacterial hydrogel useful in preparing wound dressing, comprises mixing collagen, acetic acid, Artemisia argyi essential oil solution, graphene oxide solution and quaternized chitosan solution, cross-linking, washing cross-linked material with water, refrigerating and freeze-drying.
  • 专利号:   CN116036359-A
  • 发明人:   GUO H, CHEN X, YANG J, PENG X, XIONG S, SUN Z, XU Q, WU D, ZHOU C, YANG Y, HU K
  • 专利权人:   WUHAN THIRD HOSPITAL
  • 国际专利分类:   A61L026/00
  • 专利详细信息:   CN116036359-A 02 May 2023 A61L-026/00 202349 Chinese
  • 申请详细信息:   CN116036359-A CN10060476 16 Jan 2023
  • 优先权号:   CN10060476

▎ 摘  要

NOVELTY - Preparing antibacterial hydrogel, comprises (a) adding collagen, acetic acid, Artemisia argyiessential oil solution, graphene oxide solution and quaternized chitosan solution into the test tube to obtain Col-GEO-GO-QCS solution; (b) mixing the solution in the test tube evenly under the assistance of ultrasound, placing into a hollow cylinder mold, refrigerating in -20℃, and freeze-drying; (c) placing the freeze-dried material in 95% ethanol, adding a cross-linking agent, and cross-linking at room temperature; and (d) washing the cross-linked material with water, refrigerating in -20℃, and freeze-drying. USE - The antibacterial hydrogel is useful in preparation of wound dressing (claimed). ADVANTAGE - The preparation condition is simple and mild, and the prepared antibacterial hydrogel has loose pores, good antibacterial property and mechanical property. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for antibacterial hydrogel.