▎ 摘　　要

NOVELTY - System (1000) comprises an applicator (2000) including a needle configured to puncture a subject's skin to draw a physiological sample, a first actuating lever configured to move from an undeployed position to a deployed position, and a second actuating lever configured to move from an undeployed position to a deployed position, a latch configured to maintain the second actuating lever in a locked position to inhibit movement, when the first actuating lever is in the undeployed position and configured to be released upon actuation of the first actuating lever to allow actuation of the second actuating lever and. A dermal patch (1002) configured for coupling to the applicator and including sample collection chamber (1016), a fluid reservoir configured to store a processing fluid, a sample collection chamber configured to receive the processing fluid and the physiological sample. The applicator includes a housing (2004). USE - Dermal patch system for collecting a physiological sample, such as blood and interstitial fluid. ADVANTAGE - The system and method can be utilized to collect and store a physiological sample (e.g., blood, interstitial fluid, etc.) and/or detect a target analyte (e.g., a biomarker) in a collected physiological sample. DETAILED DESCRIPTION - System comprises an applicator including a needle configured to puncture a subject's skin to draw a physiological sample, a first actuating lever configured to move from an undeployed position to a deployed position, and a second actuating lever configured to move from an undeployed position to a deployed position, a latch configured to maintain the second actuating lever in a locked position to inhibit movement thereof when the first actuating lever is in the undeployed position and configured to be released upon actuation of the first actuating lever to allow actuation of the second actuating lever and. A dermal patch configured for coupling to the applicator and including a fluid reservoir configured to store a processing fluid, a sample collection chamber configured to receive the processing fluid and the physiological sample. The applicator is configured to cause the needle to puncture the subject's skin to draw the physiological sample when the first actuating lever is moved from the undeployed lever position to the deployed lever position and cause the processing fluid to be released from the fluid reservoir when the second actuating lever is moved from the undeployed position to the deployed position. DESCRIPTION OF DRAWING(S) - The drawing shows an applicator and a dermal patch. 1000System 1002Dermal patch 1016Sample collection chamber 2000Applicator 2004Housing