• 专利标题:   Spunlaced electrostatic spinning nano fiber facial mask comprises facial mask base cloth, electrostatic spinning fiber containing nutrient solution (composed of e.g. bone collagen peptide powder, Bletilla striata and glycerol) and electrostatic spinning thermoplastic polyurethane material.
  • 专利号:   CN116196223-A
  • 发明人:   LI Y, SU Z, LAN H
  • 专利权人:   UNIV SHUNDE HOSPITAL GUANGZHOU CHINESE
  • 国际专利分类:   A61K008/02, A61K008/34, A61K008/65, A61K008/73, A61K008/86, A61K008/9789, A61K008/9794, A61P029/00, A61Q017/00, A61Q019/00, A61Q019/02, A61Q019/08, D01D005/00
  • 专利详细信息:   CN116196223-A 02 Jun 2023 A61K-008/02 202355 Chinese
  • 申请详细信息:   CN116196223-A CN10098765 10 Feb 2023
  • 优先权号:   CN10098765

▎ 摘  要

NOVELTY - Spunlaced electrostatic spinning nano fiber facial mask, comprises facial mask base cloth (3), electrostatic spinning fiber containing nutrient solution (2) and electrostatic spinning thermoplastic polyurethane (TPU) material (1); where the electrostatic spinning fiber containing nutrient solution contains 30-50 pts. wt. bone collagen peptide powder, 5-10 pts. wt. thickener, 6-8 pts. wt. Bletilla striata, 6-8 pts. wt. radix paeoniae alba, 10-15 pts. wt. blueberry, 5-10 pts. wt. ginseng, 5-10 pts. wt. kiwi fruit, 5-10 pts. wt. hyaluronic acid, 10-15 pts. wt. sodium carboxymethyl cellulose, 5-10 pts. wt. Aloeliquid extract, 10-15 pts. wt. glycerol, 5-10 pts. wt. butanediol, and 60-80 pts. wt. water, obtained by electrostatic spinning. USE - Spunlaced electrostatic spinning nano fiber facial mask. ADVANTAGE - The nano fiber has great specific surface area and excellent porosity, which greatly improves the load amount of the active ingredient in the mask; and has perfect application and biocompatibility, the active ingredient can be fully skin contact and quickly permeate into the skin then the facial mask is solid, not adding liquid component, reducing environment polluting serum in the manufacturing, and not adding preservative, without stimulation to the skin. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for preparation method of spunlaced electrostatic spinning nano fiber facial mask, comprising: (1) taking 10-15 pts. wt. fresh and clean blueberry, 5-10 pts. wt. ginseng, 5-10 pts. wt. kiwi fruit, drying until there is no water, juicing and pulping, ultrasonically extracting at 30-50℃ for 30-40 minutes under the condition of 50-100 W, filtering by 100-300 μm gauze for 20-30 minutes under the condition of 1000-4000 revolutions/minute (rpm), removing the precipitate, taking the upper layer liquid, and transferring to the stirring cylinder, adding porous graphene oxide into the stirring cylinder to rotate for 10-20 minutes at 2000-3000 rpm, adding 1-2 times the volume of porous graphene oxide to the centrifuged supernatant of blueberry, ginseng, kiwi fruit so that anthocyanins can be impregnated into the interior of porous graphene oxide to obtain an inclusion solution; (2) providing Bletilla striata, radix paeoniae alba, adding 10-20 volume times of water, percolating for 5-10 hours, repeating for 2-3 times, mixing the filtrate, then adding 10-20 times of water, ultrasonicating at frequency of 100-120 Hz for 2-3 times, each time for 20-40 minutes, concentrating to the same quality as the input medicinal materials, mixing the filtrate, adding activated carbon which is 3-5% of the total medicinal material mass, stirring for 40-50 minutes at 42 ℃, and filtering; (3) mixing the product obtained in step (1) and (2), placing into colloid mill, grinding for 10-15 minutes, the average particle diameter of the mixture is less than 320 μm; placing the mixture into high shear dispersing emulsifying machine, shearing for 10-15 minutes, where the average grain diameter of the mixture is between 150-300 μm, spraying and drying the mixture into powder, at this time, obtaining the ultra-micro powder; (4) dissolving 0.5-1.5 pts. wt. hyaluronic acid in the mixed solution of deionized water and formic acid, where the weight ratio of the deionized water and the formic acid is 20: 60, stirring uniformly to obtain 0.5-2 wt.% hyaluronic acid solution; then adding the step (3) ultramicro powder, sodium carboxymethyl cellulose, glycerol, bone collagen peptide powder, Aloeliquid extract to the hyaluronic acid solution to obtain the inner core spinning solution A containing functional component, (5) dissolving 0.5-2 pts. wt. collagen in hexafluoroisopropanol, stirring to dissolve, preparing into 0.5-3 wt.% collagen solution, obtaining shell layer spinning solution B; (6) transferring the inner core spinning solution A containing the functional component to the inner needle tube of the electrostatic spinning device, transferring the shell spinning solution B to the outer needle tube of the electrostatic spinning device, spinning, where the coaxial electro-spinning experiment device comprises an injection pump, a high voltage power supply, a direct current high voltage generator 60kV, 3mA, the inner core spinning liquid A is pushed out from the inner needle tube at a speed of 0.1 ml/hour; the shell layer spinning liquid B is pushed out at a speed of 1.2 ml/hour from the gap between the outer needle tube, applying 20kV voltage to the coaxial needle tube and the receiving plate, the receiving distance is 15 cm, the environment temperature is 26 ℃, and vacuum drying for 24 hours to obtain the nano fiber facial mask. DESCRIPTION OF DRAWING(S) - The drawing shows a spunlaced electrostatic spinning nano fiber facial mask structure schematic diagram. 1Electrostatic spinning tpu material 2Electrostatic spinning fiber containing nutrient solution 3Mask base cloth