• 专利标题:   Preparation of anti-tumor hydrogel involves uniformly mixing adriamycin graphene oxide solution and sericin solution, mixing gelatin solution, adding glutaraldehyde, and reacting.
  • 专利号:   CN104306325-A, CN104306325-B
  • 发明人:   CAI H, GUO C, JIA J, JIANG M, WU Q, YAN H
  • 专利权人:   UNIV JIANGSU SCI TECHNOLOGY
  • 国际专利分类:   A61K031/704, A61K047/42, A61K009/06, A61P035/00, A61K047/04
  • 专利详细信息:   CN104306325-A 28 Jan 2015 A61K-009/06 201522 Pages: 8 Chinese
  • 申请详细信息:   CN104306325-A CN10543601 14 Oct 2014
  • 优先权号:   CN10543601

▎ 摘  要

NOVELTY - An anti-tumor hydrogel is prepared by uniformly mixing adriamycin graphene oxide solution and 0.5-10% (w/v) sericin solution to obtain mixed solution, mixing 5-10% (w/v) gelatin solution, adding glutaraldehyde, and reacting at 20-40 degrees C for 20 minutes to 12 hours in which volume ratio of graphene oxide solution and sericin is 1:(2-5), volume ratio of mixed solution and gelatin solution is (0.5-1.5):1, and mass ratio of sericin and glutaraldehyde is 1:(0.05-0.25). USE - Preparation of anti-tumor hydrogel (claimed). ADVANTAGE - Product enhances anti-tumor effect and reduces painful effect of drugs.