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  • 专利标题:   Preparation of poly-ionic liquid modified reduced graphene oxide-loaded doxorubicin used for preparing anti-tumor drug by loading poly-ionic liquid-reduced graphene oxide composite material with doxorubicin, and freeze-drying.
  • 专利号:   CN107049989-A, CN107049989-B
  • 发明人:   LIU Y, WU H, CHEN L, LI L, LIU B
  • 专利权人:   UNIV LIAONING, LI L
  • 国际专利分类:   A61K031/704, A61K047/04, A61K009/50, A61K009/51, A61P035/00
  • 专利详细信息:   CN107049989-A 18 Aug 2017 A61K-009/51 201774 Pages: 10 Chinese
  • 申请详细信息:   CN107049989-A CN10332868 12 May 2017
  • 优先权号:   CN10332868

▎ 摘　　要

NOVELTY - Preparation of poly-ionic liquid (PIL) modified reduced graphene oxide (RGO)-loaded doxorubicin (DOX) comprises selecting PIL-RGO composite material as carrier material, loading with DOX, and freeze-drying. USE - Method for preparation of poly-ionic liquid (PIL) modified reduced graphene oxide (RGO)-loaded doxorubicin used for preparing anti-tumor drug (all claimed). ADVANTAGE - The product has good water solubility, enhanced stability, pH-sensitive release characteristics, and slow release effect which prolongs DOX residence time in the body enhancing its curative effect.