▎ 摘　　要

NOVELTY - Detecting disease state in a subject comprises obtaining liquid biological sample from the subject and placing it into a container, contacting the liquid biological sample with a first chemical sensor element, the first chemical sensor element comprising discrete graphene varactors, and sensing and storing capacitance of each of the discrete graphene varactors to obtain a first sample data set. USE - The method is useful for detecting disease state in a subject. ADVANTAGE - The method provides optimal binding of chemical compounds to corresponding discrete graphene varactors. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for system for detecting a disease state comprising a container comprising a housing adapted to contain a liquid biological sample of a subject, the housing defining a headspace comprising a volume of a gas, first chemical sensor element configured to be contacted with the liquid biological sample, the first chemical sensor element comprises discrete graphene varactors, and a sensing device configured to interface with the first chemical sensor element, the sensing device further configured to sense a capacitance of the plurality of discrete graphene varactors.