• 专利标题:   Sustained release microsphere used for resisting tumor, comprises graphene oxide and medicine.
  • 专利号:   CN106176620-A
  • 发明人:   NIE H, LIU X, LIU L
  • 专利权人:   UNIV DONGHUA
  • 国际专利分类:   A61K031/704, A61K047/04, A61K009/16, A61P035/00
  • 专利详细信息:   CN106176620-A 07 Dec 2016 A61K-009/16 201711 Pages: 7 Chinese
  • 申请详细信息:   CN106176620-A CN10638299 05 Aug 2016
  • 优先权号:   CN10638299

▎ 摘  要

NOVELTY - Sustained release microsphere comprises graphene oxide and medicine in mass ratio of 1:0.5-1:5. USE - Sustained release microsphere used for resisting tumor. ADVANTAGE - The sustained release microsphere pH-sensitive release and good practical value. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for preparing sustained release microsphere, which involves: (A) stirring graphene oxide and medicine in phosphate buffer solution ultrasonically at room temperature; (B) centrifuging obtained mixture; (C) freezing and drying centrifuged material to obtain graphene oxide medicine compound; (D) dissolving graphene oxide medicine compound in water ultrasonically to obtain product; (E) coating product using polyfluortetraethylene filter film; and (F) collecting and drying product.