• 专利标题:   Nitrogen-ion-implanted three-dimensional self-assembled graphene useful as tissue support biomaterial, has graphene sheet structure with preset diameter and magnitude, and comprises preset amount of nitrogen.
  • 专利号:   CN104803379-A
  • 发明人:   CAO Y, HOU X, LI D, ZHAO M, LI X, LIU X
  • 专利权人:   UNIV TIANJIN NORMAL
  • 国际专利分类:   A61L031/02, A61L031/14, C01B031/04, C23C014/06, C23C014/48
  • 专利详细信息:   CN104803379-A 29 Jul 2015 C01B-031/04 201567 Pages: 15 Chinese
  • 申请详细信息:   CN104803379-A CN10189628 21 Apr 2015
  • 优先权号:   CN10189628

▎ 摘  要

NOVELTY - Nitrogen-ion-implanted three-dimensional self-assembled graphene has graphene sheet structure with a diameter of 5-15 mu m and a magnitude of 2 mu m by observation, and comprises 0.6-4.24% nitrogen. USE - Nitrogen-ion-implanted three-dimensional self-assembled graphene is useful as tissue support biomaterial (claimed). ADVANTAGE - The nitrogen-ion-implanted three-dimensional self-assembled graphene, when used as tissue support biomaterial, increases cell adhesion and growth, improves hydrophilicity and protein adsorption, and has excellent biocompatibility. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following: (1) preparation of nitrogen-ion-implanted three-dimensional self-assembled graphene, which involves slicing three-dimensional self-assembled graphene to 2-3.2 mm, freezing at 0 degrees C or less for 12 hours or more, and finally at -40 degrees C to -80 degrees C and less than 10 Pa for 10-48 hours, and injecting 1x 1016-1x 1020 nitrogen ions at 5-25 keV; and (2) use of nitrogen-ion-implanted three-dimensional self-assembled graphene as tissue support biomaterial.