• 专利标题:   Preparing drug loaded-fluorescent graphene quantum dots (GQDs) embedded mesoporous silica nanostructure for image guided solid tumor ablation, by adding emissive GQDs on silica coated N-cetyltrimethylammonium bromides (CTAB) surfactant, hydrolyzing and condensing, centrifuging, and removing CTAB.
  • 专利号:   IN202121021279-A
  • 发明人:   PRASAD R, JAIN N K, JADHAV M, SRIVASTAVA R, YADAV A S, GORAIN M, KUNDU G C
  • 专利权人:   INDIAN INST TECHNOLOGY BOMBAY, NAT CENT CELL SCI
  • 国际专利分类:   A61B018/00, B82Y030/00, B82Y040/00, C01B037/02, C09K011/65
  • 专利详细信息:   IN202121021279-A 18 Nov 2022 A61B-018/00 202204 Pages: 51 English
  • 申请详细信息:   IN202121021279-A IN21021279 11 May 2021
  • 优先权号:   IN21021279

▎ 摘  要

NOVELTY - Method for preparing drug loaded-fluorescent graphene quantum dots (GQDs) embedded mesoporous silica nanostructure, involves adding emissive GQDs on a silica coated N-cetyltrimethylammonium bromides (CTAB) surfactant, determining a completion of hydrolysis and condensation of the added aminated silica precursors over the GQDs attached CTAB surfactant, obtaining a fluorescent GQDs embedded silica nanostructure by centrifugation, removing the CTAB surfactant from the fluorescent GQDs embedded silica nanostructure to obtain the fluorescent GQDs embedded mesoporous silica nanostructure, and obtaining the drug loaded-fluorescent GQDs embedded mesoporous silica nanostructure. USE - The method is used for preparing drug loaded-fluorescent graphene quantum dots (GQDs) embedded mesoporous silica nanostructure for image guided solid tumor ablation as powerful nanotheranostic agent for localized tumor imaging/diagnosis and therapy. ADVANTAGE - None given.