▎ 摘　　要

NOVELTY - Preparing surface-enhanced Raman spectroscopy (SERS) substrates based on novel composites, comprises e.g. (i) synthesizing gold-silver nanoparticle (Au-Ag NPs) with core-shell structure, (ii) synthesizing silver nanoparticle (Ag NPs), (iii) synthesizing zeolitic imidazolate framework-67 mediated silver nanoparticle (Ag NPs@ZIF-67), dispersing in ethanol, adding nickel nitrate hexahydrate, placing the mixed solution in water bath with heating and stirring, collecting precipitate by centrifugation, drying to obtain AgNPs@CoNi-LDH, (iv) dispersing Ag NPs@CoNi-LDH in ethanol, adding graphene oxide dispersion, heating the mixed solution and stirring, collecting the precipitate by centrifugation, washing, and dispersing in ethanol to obtain ethanol dispersion of Ag NPs@CoNi-LDH@GO, (v) drop-coating the ethanol dispersion of Au@Ag NPs on mold, air-drying, then drop-coating the layer of ethanol dispersion of Ag NPs@CoNi-LDH@GO on mold, air drying and removing mold to obtain final product. USE - The surface-enhanced Raman spectroscopy substrate is useful for simultaneous rapid detection of methyl sulfide and 2,4-di-tert-butylphenol. ADVANTAGE - The surface-enhanced Raman spectroscopy substrateas strong adsorption capacity. DETAILED DESCRIPTION - Preparing surface-enhanced raman spectroscopy (SERS) substrates based on novel composites, comprises (i) synthesizing gold-silver nanoparticle (Au-Ag NPs) with core-shell structure, (ii) synthesizing silver nanoparticle (Ag NPs), (iii) synthesizing zeolitic imidazolate framework-67 mediated silver nanoparticle (Ag NPs@ZIF-67), dispersing in ethanol, adding nickel nitrate hexahydrate, placing the mixed solution in water bath at 85degrees Celsius for 1 hour with heating and stirring until the solution turned green, collecting precipitate by centrifugation, drying at 50degrees Celsius for 12 hours to obtain AgNPs@CoNi-LDH, (iv) dispersing Ag NPs@CoNi-LDH in ethanol, adding 2 mg/ml graphene oxide dispersion, heating the mixed solution in water bath at 60degrees Celsius and stirring for 2 hours, collecting the precipitate by centrifugation, washing with ethanol, and dispersing in ethanol to obtain ethanol dispersion of Ag NPs@CoNi-LDH@GO, and (v) drop-coating the ethanol dispersion of Au@Ag NPs on mold, air-drying, then drop-coating layer of ethanol dispersion of Ag NPs@CoNi-LDH@GO on mold, and removing mold to obtain final product. An INDEPENDENT CLAIM is also included for surface-enhanced Raman spectroscopy substrates based on novel composites comprises Au@Ag NPs layer and Ag NPs@CoNi-LDH@GO layer covering the surface of the Au@Ag NPs layer.