• 专利标题:   Bio-mineralized graphene-modified calcium carbonate particles used in cosmetics, comprise silk fibroin, chitosan, graphene and calcium carbonate.
  • 专利号:   CN109010081-A
  • 发明人:   XU Y
  • 专利权人:   DONGGUAN LIANZHOU INTELLECTUAL PROPERTY
  • 国际专利分类:   A61K008/02, A61K008/19, A61K008/64, A61K008/73, A61Q019/08, A61Q019/00, A61Q017/00, C01F011/18
  • 专利详细信息:   CN109010081-A 18 Dec 2018 A61K-008/02 201921 Pages: 7 Chinese
  • 申请详细信息:   CN109010081-A CN10809924 23 Jul 2018
  • 优先权号:   CN10809924

▎ 摘  要

NOVELTY - A bio-mineralized graphene-modified calcium carbonate particles comprise silk fibroin, chitosan, graphene and calcium carbonate. The silk fibroin and chitosan constitute a porous particle carrier. The graphene and calcium carbonate are deposited in the pores of the porous particle carrier. USE - Bio-mineralized graphene-modified calcium carbonate particles used in cosmetics (claimed). DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for preparation of bio-mineralized graphene-modified calcium carbonate particles, which involves mixing silk fibroin solution and chitosan solution, adding alcohol solution, heating, evaporating, concentrating to obtain concentrated silk fibroin/chitosan composite solution, adding solution of calcium oxide to graphene oxide solution, mixing uniformly, adding hydrazine hydrate, heating, reducing to obtain graphene-modified calcium ion solution, adding concentrated silk fibroin/chitosan composite solution, stirring, spray-drying to obtain porous composite precursor microspheres, soaking in urea solution at low temperature, and heat-treating.