• 专利标题:   New guanidine functionalized graphene compound, used as solid phase extraction material and used in the selective enrichment of phosphorylated peptides.
  • 专利号:   CN104109187-A, CN104109187-B
  • 发明人:   BAI Y, LI L, LIU H, XU L
  • 专利权人:   UNIV PEKING
  • 国际专利分类:   C01B031/04, C07K001/14, C07K014/00, C07K007/06, C07K007/08, C01B032/184
  • 专利详细信息:   CN104109187-A 22 Oct 2014 C07K-001/14 201503 Pages: 19 Chinese
  • 申请详细信息:   CN104109187-A CN10314563 03 Jul 2014
  • 优先权号:   CN10314563

▎ 摘  要

NOVELTY - Guanidine functionalized graphene compound of (I), is new. USE - Guanidine functionalized graphene compound used as solid phase extraction material and used in the selective enrichment of phosphorylated peptides. DETAILED DESCRIPTION - Guanidine functionalized graphene compound of formula (I), is new. G=graphene substrate; and n=2-8. An INDEPENDENT CLAIM is included for a method for preparing guanidine functionalized graphene compound, which involves: (A) taking oxidized graphene surface with carboxyl group to obtain graphene acyl chloride and then burning the obtained material with 2-8C diamino compound (II) to obtain compound (III); (B) dispersing the compound (III) in water and then adding ortho-methylisourea to the dispersed material; and (C) heating the obtained material to obtain the guanidino functionalized graphene compound (I), where the pH of reaction solution is 10-12.