▎ 摘 要
NOVELTY - Zirconium dioxide inorganic molecular imprinted acetaminophen electrochemical transistor sensor comprises a source electrode, a drain electrode and a grid electrode. The source electrode and the drain electrode are set on the bottom layer is a chromium layer of the gold layer. A source electrode is set between the channel between drain electrode is a single layer. The graphene the grid is the target molecule. The gold nano particles/graphene composite material is imprinted carrier, the zirconia oxychloride is inorganic functional monomer, the molecular imprinting polymer is formed on the glassy carbon electrode by cyclic voltammetry electropolymerization method, eluting the target molecules to obtain the glass-y carbon electrodes modified by zirconium dioxide-gold nano-particle/graphic/molecularly imprinted composite material. USE - Zirconium dioxide inorganic molecularly imprinted acetaminophen electrochemical transistor sensor. ADVANTAGE - The zirconium dioxide inorganic molecularly imprinted acetaminophen electrochemical transistor sensor has high sensitivity, low detection limit and high selectivity, and can realize accurate determination of paracetamol in complex urine environment. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for: 1. a method for preparing a zirconia inorganic molecularly imprinted acetaminophen electrochemical transistor sensor, which involves: (a) plating orderly chromium layer and a gold layer on the glass substrate, selecting respectively as the source electrode and the drain electrode; (b) adopting the method for wet method transfer, transferring the monolayer graphene between the selected source electrode and the drain electrode as channel; (c) taking acetaminophen as the target molecule, using gold nanoparticle/graphene composite as the imprinted carrier, using zirconium oxychloride as the inorganic functional monomer; (d) forming molecularly imprinted polymer on glassy carbon electrodes by electropolymerization, eluting target molecule to prepare zirconia-gold nanoparticles/graphene/molecularly imprinted composite modified glassy carbon electrodes as gates; and (e) using together gate, the source, the drain and the channel as a combination, which is a molecularly imprinted electrochemical transistor sensor for acetaminophen; and 2. a method for detecting acetaminophen by the zirconium dioxide inorganic molecularly imprinted acetaminophen electrochemical transistor sensor, which involves: (a)immersing the electrochemical transistor sensor in the buffer solution, detecting the channel current value I0when reaching equilibrium, as a blank control: (b) immersing the electrochemical transistor sensor in buffer solutions of different concentrations of acetaminophen, detecting the channel current value I when reaching equilibrium, subtracting the blank to obtain the current change value ΔI=I-I0of the channel of the molecularly imprinted transistor sensor; (c) taking the channel current change value ΔI of the electrochemical transistor sensor in buffer solutions of different concentrations of acetaminophen as the ordinate, the logarithm value of paracetamol concentration as abscissa; and (d)establishing calibration curve for detecting paracetamol by the electrochemical transistor sensor to realize the quantitative analysis and detection of paracetamol in the liquid to be tested.