• 专利标题:   Preparing composite bacteriostat, comprises ultrasonically dispersing modified starch-sodium phytate nanoparticles and graphene oxide modified amoxicillin in ethanol solution and microwave reacting.
  • 专利号:   CN108770864-A
  • 发明人:   WANG F, DU H
  • 专利权人:   WUHU DEXIN AUTO PARTS CO LTD
  • 国际专利分类:   A01N059/00, A01N043/90, A01N057/12, A01P001/00
  • 专利详细信息:   CN108770864-A 09 Nov 2018 A01N-059/00 201883 Pages: 9 Chinese
  • 申请详细信息:   CN108770864-A CN10621706 15 Jun 2018
  • 优先权号:   CN10621706

▎ 摘  要

NOVELTY - Preparing composite bacteriostat, comprises (i) dissolving starch in water, adjusting pH of system to 5.3-6.1 to obtain a starch solution, adding sodium phytate to starch solution, and stirring for 2-5 hours to obtain starch-sodium phytate nanoparticles, (ii) uniformly mixing calcined diatomaceous earth, silane coupling agent and starch-sodium phytate nanoparticles in water and stirring at 60-80 degrees C for 0.5-3 hours to obtain modified starch-sodium phytate nanoparticles, (iii) ultrasonically dispersing graphene oxide in ethanol for 15-30 minutes to obtain a graphene suspension, adjusting pH of system to 7.6-8.5, then adding 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide, N-hydroxysuccinimide and amoxicillin, stirring and reacting for 24-48 hours to obtain graphene oxide modified amoxicillin and (iv) ultrasonically dispersing the modified starch-sodium phytate nanoparticles and graphene oxide modified amoxicillin in ethanol solution for 3-8 minutes and microwave reacting for 1-5 minutes. USE - The composite bacteriostat is useful in an automobile interior (claimed). ADVANTAGE - The composite bacteriostat has long-lasting bacteriostatic and antibacterial effects, can effectively inhibit the growth of indoor bacteria, has no toxic side effects on human body, and is environmentally friendly. DETAILED DESCRIPTION - Preparing composite bacteriostat, comprises (i) dissolving starch in water, then adjusting pH of the system to 5.3-6.1 to obtain a starch solution, adding sodium phytate to the starch solution, and stirring for 2-5 hours to obtain starch-sodium phytate nanoparticles, (ii) uniformly mixing calcined diatomaceous earth, silane coupling agent and the starch-sodium phytate nanoparticles in water and stirring at 60-80 degrees C for 0.5-3 hours to obtain modified starch-sodium phytate nanoparticles, (iii) ultrasonically dispersing graphene oxide in ethanol for 15-30 minutes to obtain a graphene suspension, adjusting the pH of the system to 7.6-8.5, then adding 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide, N-hydroxysuccinimide and amoxicillin, stirring and reacting for 24-48 hours to obtain graphene oxide modified amoxicillin and (iv) ultrasonically dispersing the modified starch-sodium phytate nanoparticles and graphene oxide modified amoxicillin in ethanol solution for 3-8 minutes and microwave reacting for 1-5 minutes. An INDEPENDENT CLAIM is also included for composite bacteriostat prepared by the above mentioned method.