▎ 摘　　要

NOVELTY - Biosensor comprises a substrate, a graphene layer disposed on the substrate, and a binding site bonded to the graphene layer, the binding site including an antibody configured to bind a SARS-CoV-2 spike glycoprotein. USE - The biosensor is useful for: the sample comprises at least one of saliva or blood; the detect a spike glycoprotein comprises forming a biosensor (all claimed); useful in various aspects of diagnosing, analyzing, and identifying at least one biomarkers associated with vims; treating and/or monitoring treatment of at least one diseases and conditions associated with viral infection. No biological data given. ADVANTAGE - The biosensor: have quickly and directly detecting various analytes, markers, and biomarkers; and improvement in at least one markers, symptoms, indicators, or signs of the disease or condition. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for method to detect a spike glycoprotein comprises forming a biosensor by depositing at least one graphene layer on a substrate, where the at least one graphene layer includes one or more binding sites, forming an electrical contact on the at least one graphene layer or the substrate, and attaching an antibody to the at least one graphene layer, where the antibody is configured to bind a target from a sample.