• 专利标题:   Composite hydrogel is useful for preparing chronic wound repair product, comprises chitosan and nitrogen-doped graphene which are chemically crosslinked.
  • 专利号:   CN109021255-A
  • 发明人:   LIN Q
  • 专利权人:   HUNAN GONSION GRAPHITE TECHNOLOGY CO LTD
  • 国际专利分类:   C08J003/075, C08J003/24, C08L005/08, C08K003/04, C08K005/29, C08K005/3415, A61L031/04, A61L031/14
  • 专利详细信息:   CN109021255-A 18 Dec 2018 C08J-003/075 201922 Pages: 5 Chinese
  • 申请详细信息:   CN109021255-A CN10557405 01 Jun 2018
  • 优先权号:   CN10557405

▎ 摘  要

NOVELTY - Composite hydrogel comprises chitosan and nitrogen-doped graphene chitosan and nitrogen-doped graphene which are chemically crosslinked. The molecular weight of chitosan is 8000-12000 daltons and the mass ratio of nitrogen-doped graphene to chitosan is 0.1:1-5:1. USE - The hydrogel is useful for preparing chronic wound repair product (claimed). ADVANTAGE - The hydrogel has good biocompatibility and high mechanical strength, is non-irritating to tissues and simple, improves local micro-environment of the wound, accelerates wound healing and prevents infection. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for preparing the hydrogel comprising (i) dissolving chitosan in water, sequentially adding crosslinking agent and nitrogen-doped graphene and stirring under sealing condition, and (ii) dialyzing the solution obtained in step (i) and pouring the dialyzed solution into a mold and irradiating under sealed conditions.