▎ 摘　　要

NOVELTY - The method comprises: generating (1002) holes in graphene in a periodic way to create a graphene nanomesh with a patterned array of holes in terms of size and lattice constant; (1004) passivating an edge of each of the holes of the graphene nanomesh to allow functionalization of the graphene nanomesh; and functionalizing (1006) the passivated edge of each of the holes with a chemical compound that facilitates chemical binding of a receptor of a target molecule to the edge of the holes to increase a conductance of the graphene nanomesh and allowing the target molecule to bind to the receptor. USE - The method is useful for producing a graphene nanomesh based charge sensor (claimed) such as a biosensor, a chemical sensor, a gas sensor, an explosive sensor and a glucose sensor. ADVANTAGE - The method is capable of efficiently producing the graphene nanomesh based charge sensor with high sensitivity and stability. DETAILED DESCRIPTION - The method comprises: generating (1002) holes in graphene in a periodic way to create a graphene nanomesh with a patterned array of holes in terms of size and lattice constant; (1004) passivating an edge of each of the holes of the graphene nanomesh to allow functionalization of the graphene nanomesh; and functionalizing (1006) the passivated edge of each of the holes with a chemical compound that facilitates chemical binding of a receptor of a target molecule to the edge of the holes to increase a conductance of the graphene nanomesh, allowing the target molecule to bind to the receptor and causing a charge to be transferred to the graphene nanomesh to produce a graphene nanomesh based charge sensor for the target molecule. Each hole has a size of 5-20 nm. The patterned array of holes has a pitch of 3x to 6x. The size of each hole binds with the receptor of the target molecule. The receptor is a molecule that: reacts with the graphene nanomesh yielding functionalized graphene nanomesh; and chemically binds to the target molecule, irrespective of the size of the target molecule. The method further comprises controlling a density of receptor sites by controlling a characteristic of the patterned array of holes of the graphene nanomesh. A reaction is between the target molecule and the receptor leads to a net charge transfer to the graphene nanomesh for n-doping the graphene nanomesh. An INDEPENDENT CLAIM is included for a graphene nanomesh based charge sensor. DESCRIPTION OF DRAWING(S) - The diagram shows a flowchart of a method for producing a graphene nanomesh based charge sensor. Generating holes in graphene to create a graphene nanomesh (1002) Passivating an edge of each hole of the graphene nanomesh (1004) Functionalizing the passivated edge of each hole with a chemical compound. (1006)