• 专利标题:   Catalyzing and synthesizing (R)-1-[3,5-bis(trifluoromethyl)] acetophenone by infrared light-driven carbon quantum dot-based photoenzyme catalyst, involves preparing graphene quantum dots and aldehyde and ketone reductase aggregates, and adding reaction solvent followed by heating and drying.
  • 专利号:   CN115386604-A
  • 发明人:   LI X, WANG A, GAO P
  • 专利权人:   UNIV HANGZHOU NORMAL
  • 国际专利分类:   B01J021/18, C12N009/04, C12P007/22
  • 专利详细信息:   CN115386604-A 25 Nov 2022 C12P-007/22 202311 Chinese
  • 申请详细信息:   CN115386604-A CN10770487 30 Jun 2022
  • 优先权号:   CN10770487

▎ 摘  要

NOVELTY - Catalyzing and synthesizing R-3,5-BTPE involves preparing graphene quantum dots and aldehyde and ketone reductase aggregates by mechanical stirring to prepare a composite hybrid and adding the reaction solvent, NADP+, photoenzyme catalyst r-graphene quantum dots (GQDs)/aldehyde and ketone reductase (AKR)-cross-linked enzymes (CLEs), 3,5-bis(trifluoromethyl)acetophenone into the reactor and reacting under the illumination of xenon lamp. The supernatant of the reaction liquid is taken. The supernatant is extracted with anhydrous n-hexane followed by heating and spin drying under reduced pressure to obtain pure (R)-1-3,5-bis(trifluoromethyl) acetophenone (R-3,5-BTPE). USE - Catalyzing and synthesizing R-3,5-BTPE by infrared light-driven carbon quantum dot-based photoenzyme catalyst. ADVANTAGE - The method greatly reduces the cost, has high catalytic efficiency, mild reaction conditions, simple operation, easy recovery and recycling, and is suitable for large-scale industrial production and application and environmentally friendly.