▎ 摘　　要

NOVELTY - Scaffold material comprises graphene nanoparticles, porous silk fibroin scaffold and ceramic implant segment. The graphene nanoparticles are loaded on the porous silk fibroin scaffold, and the ceramic implant segment is connected to the porous silk fibroin scaffold through fibronectin. USE - Scaffold material for mesenchymal stem cells inducing osteogenic differentiation in vitro, and cultivation of mesenchymal stem cells (claimed). ADVANTAGE - The scaffold material has unique biocompatibility, mechanical strength characteristics and biodegradation characteristics, promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells, and contributes to the formation of osteogenic differentiation of stem cells. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a preparation method for scaffold material, which involves extracting silkworm cocoons in 0.02M sodium carbonate solution and dissolving in 9.3M lithium bromide solution, dialyzing in distilled water and centrifuging to obtain 2.5g/mL silk fibroin solution, pre-mixing glycerol solution with the silk fibroin solution at a weight ratio of 3:7, freeze-drying and slicing resulting mixture to obtain silk fibroin, where obtained silk fibroin is made of natural clay as a binder to press the silk fibroin into a hollow cylindrical shape, synthesizing graphite particles by the optimized Hummers method, obtaining graphene rice particles by grinding, combining obtained graphene rice particles with the porous silk fibroin scaffold, and the ceramic implant segments are connected by fibronectin to obtain the scaffold material, inoculating human bone marrow mesenchymal stem cells to the scaffold material at a cell count of 105-106, and culturing in an osteogenic differentiation microenvironment. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic view of scaffold material.