• 专利标题:   Preparing graphene oxide reinforced collagen film corneal repair material repairing and replacing clinical ophthalmic surgical suture and as tissue engineering material, involves dissolving bovine tendon collagenin acetic acid.
  • 专利号:   CN113648460-A
  • 发明人:   LIU Y
  • 专利权人:   JIANGSU CHINAISRAEL IND TECHNOLOGY RES, UNIV CHANGZHOU
  • 国际专利分类:   A61L027/02, A61L027/24, A61L027/50, A61L027/58
  • 专利详细信息:   CN113648460-A 16 Nov 2021 A61L-027/24 202207 Chinese
  • 申请详细信息:   CN113648460-A CN10987282 26 Aug 2021
  • 优先权号:   CN10987282

▎ 摘  要

NOVELTY - Preparing graphene oxide reinforced collagen film corneal repair material involves dissolving bovine tendon collagenin acetic acid at 25degrees Celsius, preparing a certain concentration of collagen solution, preparing a certain concentration of graphene oxide solution, carbodiimide and N-hydroxyl succinyl solution, slowly adding the graphene oxide solution obtained to the collagen solution, adding the corresponding proportion of carbodiimide and N-hydroxyl succinyl solution, slowly stirring at a certain temperature for crosslinking reaction, naturally drying the crosslinked hydrogel to obtain product. USE - Method for preparing graphene oxide reinforced collagen film corneal repair material used for repairing and replacing clinical ophthalmic surgical suture and as tissue engineering material. ADVANTAGE - The graphene oxide reinforced collagen film corneal repair material has good mechanical property, optical performance and biological compatibility, and molding is controllable. The material is more convenient and convenient for clinical operation and application. The preparation process is simple and the device is simple.