▎ 摘 要
NOVELTY - Biofilm medical dressing comprises 0.3-3 wt.% sodium alginate, 0-1 wt.% reduced graphene oxide, 0-1 wt.% wound healing medicine, 0.01-1 wt.% trehalose, 0.01-1 wt.% polyethylene glycol, 3-7 wt.% glycerin, 1-5 wt.% propylene glycol, 1-5 wt.% 1,3-propanediol, 0.1-0.5 wt.% 1,2-hexanediol, 0.1-0.5 wt.% phenoxyethanol, 0.05-0.5 wt.% hyaluronic acid, 0.05-0.5 wt.% ascorbic acid, 0.05-0.5 wt.% collagen, and balanced amount of deionized water, in 100 wt.% total amount. USE - Biofilm medical dressing used for healing wound, applying to a smearable tear-off mask or dressing patch to applied to large wounds, repairing masks, and wound dressings (claimed). ADVANTAGE - The biofilm medical dressing can be applied to smear-type tear-off masks, large-scale wounds, repair masks, wound dressings, etc., and has low cost and degradability. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for preparing the biofilm medical dressing, which involves dissolving 0.1-1 g wound-healing drug in 5-10 mL of an alcohol solution mixed with glycerin, propylene glycol, 1,3-propanediol, 1,2-hexanediol and phenoxyethanol to obtain solution A, mixing sodium alginate, polyethylene glycol, reduced graphene oxide, trehalose, hyaluronic acid, ascorbic acid, collagen and water to obtain solution B, mixing solution A and solution B in volume ratio of 1:5, adjusting the pH to 4-6 after stirring, and obtaining biofilm medical dressing slurry, mixing the biofilm medical dressing slurry and multivalent metal salt solution at a volume ratio of 1:20, processing semi-crosslinking reaction for 1-40 minutes to obtain a biofilm medical dressing hydrogel, injecting the biofilm medical dressing slurry into mold, heating it at -20 °C to 60 °C for 0-6 hours to obtain a biofilm medical dressing, and immersing the obtained biofilm medical dressing in 1-10 wt.% polyvalent metals in the saline solution, processing cross-linking reaction for 1-40 minutes, washing surface with deionized water, and obtaining biofilm medical dressing patch with a three-dimensional porous structure through cross-linking.