▎ 摘　　要

NOVELTY - Preparing ampicillin molecularly imprinted electrochemical sensor based on graphene nanocomposite synergies comprises (i) utilizing alumina powder to polish inert electrode, and ultrasonically cleaning; (ii) using a pipette to modify 10-15 μl graphene oxide (GO) dispersion on surface of polished inert electrode, and drying, constructing a three-electrode system with inert electrode of modified GO as working electrode, placing in 0.5-1 mmol/l chloroauric acid solution, using constant potential deposition, and constant potential depositing for 250-500 seconds to obtain inert electrode modified by reduced graphene oxide-nano-gold composites (rGO-AuNPs); (iii) preparing prepolymerization solution containing template molecule ampicillin and functional monomer o-phenylenediamine; (iv) constructing a three-electrode system with inert electrode modified by rGO-AuNPs as working electrode, electropolymerizing; and (v) removing ampicillin template molecule in ampicillin MIP by elution. USE - The method is useful for preparing ampicillin molecularly imprinted electrochemical sensor based on graphene nanocomposite synergies. ADVANTAGE - The electrochemical sensor can be applied to the rapid, sensitive and specific analysis of ampicillin. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for ampicillin molecularly imprinted electrochemical sensor prepared by the above method.