• 专利标题:   Pickering emulsion used as Chlamydia trachomatis vaccine adjuvant, comprises oil-in-water emulsion comprising graphene oxide quantum dots, oil phase and aqueous phase.
  • 专利号:   CN116077640-A
  • 发明人:   CHEN H, SHI K, LI Z, ZHAO L
  • 专利权人:   UNIV SOUTH CHINA
  • 国际专利分类:   A61K039/118, A61K039/39, A61K047/04, A61P027/02, A61P031/04
  • 专利详细信息:   CN116077640-A 09 May 2023 A61K-039/39 202350 Chinese
  • 申请详细信息:   CN116077640-A CN10070541 17 Jan 2023
  • 优先权号:   CN10070541

▎ 摘  要

NOVELTY - Pickering emulsion comprises an oil-in-water emulsion comprising graphene oxide quantum dots, an oil phase and an aqueous phase. USE - The Pickering emulsion is used as a Chlamydia trachomatis vaccine adjuvant. ADVANTAGE - The Pickering emulsion uses graphene oxide quantum dots as an emulsifier, has excellent biodegradability and biocompatibility of graphene oxide quantum dots, due to the high surface area, shows high immune enhancement efficiency, slowly releases antigens in vivo and in vitro, and does not cause damage to heart, liver and kidney function of mice. The method is simple and easy to operate and cost-effective. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for: A method for preparing the Pickering emulsion, involving mixing the graphene oxide quantum dot solution, oil phase and water to obtain a mixed solution, and ultrasonically emulsifying the mixed solution under conditions to obtain the product; and An application of the Pickering emulsion as a Chlamydia trachomatis vaccine adjuvant.