• 专利标题:   Method for detecting promyelocytic leukemia PML/RAR alpha fusion gene, involves preparing Carbon dot-graphene oxide composites, constructing electrochemical DNA biosensor using methylene blue before and after hybridization to detect gene.
  • 专利号:   CN105334253-A
  • 发明人:   CHEN W, LEI Y, LIN X, LIU A, WANG P, DENG Y, ZHENG Z
  • 专利权人:   UNIV FUJIAN MEDICAL
  • 国际专利分类:   G01N027/30
  • 专利详细信息:   CN105334253-A 17 Feb 2016 G01N-027/30 201627 Pages: 16 English
  • 申请详细信息:   CN105334253-A CN10873302 03 Dec 2015
  • 优先权号:   CN10873302

▎ 摘  要

NOVELTY - A promyelocytic leukemia PML/RAR alpha fusion gene detecting method involves utilizing carbon-dots-graphene oxide composites assembled electrochemical DNA biosensor by preparing Carbon dot-graphene oxide composites, constructing electrochemical DNA biosensor using methylene blue before and after hybridization intensity of the current to achieve the detection of the target gene. USE - Method for detecting promyelocytic leukemia PML/RAR alpha fusion gene. ADVANTAGE - The constructed DNA sensor has good selectivity and high sensitivity. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for a carbon-dots-graphene oxide composites assembled electrochemical DNA biosensors.