• 专利标题:   Method for preparing antibacterial air-permeable porous graphene oxide/chitosan composite bracket, involves producing antibacterial metal salt followed by placing porous composite frame in concentrated sodium hydroxide solution.
  • 专利号:   CN103191464-A, CN103191464-B
  • 发明人:   WANG Z, GUO Y, HAN L, JIANG L, LIU M, LU X, XIE C
  • 专利权人:   UNIV SOUTHWEST JIAOTONG
  • 国际专利分类:   A61L027/20, A61L027/36, A61L027/54, A61L027/56
  • 专利详细信息:   CN103191464-A 10 Jul 2013 A61L-027/20 201381 Pages: 6 Chinese
  • 申请详细信息:   CN103191464-A CN10117027 07 Apr 2013
  • 优先权号:   CN10117027

▎ 摘  要

NOVELTY - An antibacterial air-permeable porous graphene oxide/chitosan composite bracket preparation method involves producing an antibacterial metal salt, taking carboxylated graphene oxide as an antibiotic carrier, adding reducing agent and stirring for 1-24 hours. The metal ion in the solution is reduced into a metal substance, and dialysis is carried out to obtain chitosan solution. The unreacted reducing agent is removed by graphene oxide loaded antibiotic loading antibacterial metal simple substance. The oxidized graphite is dried to obtain the carboxylation of graphene oxide powder. USE - Method for preparing an antibacterial air-permeable porous graphene oxide/chitosan composite bracket. ADVANTAGE - The method enables preparing the antibacterial air-permeable porous graphene oxide/chitosan composite bracket with better short-term antibacterial and long-term antibacterial effects, in a simple and fast manner. DETAILED DESCRIPTION - An antibacterial air-permeable porous graphene oxide/chitosan composite bracket preparation method involves producing antibacterial metal salt, taking carboxylated graphene oxide as an antibiotic carrier, adding 0.01-0.05M reducing agent and stirring for 1-24 hours. The metal ion in the solution is reduced into metal substance, and dialysis is carried out to obtain chitosan solution. The unreacted reducing agent is removed by graphene oxide loaded antibiotic loading antibacterial metal simple substance. The oxidized graphite is freezed and dried to obtain the carboxylation of graphene oxide powder, and placed in water. The solution is mixed and injected into a mold cavity. The mold is freezed and dried to obtain a porous composite frame. The porous composite frame is placed in concentrated sodium hydroxide solution to increase strength and dried to obtain the product.