• 专利标题:   System useful for measuring mechanical movements in biological sample, comprises chamber, composite film structure comprising metallic layer and polymer layer, electrical connections and central opening configured to receive biological sample.
  • 专利号:   US2022091042-A1
  • 发明人:   MERCOLA M, MOLOKANOVA E, SAVTCHENKO A, LIPOMI D J, ZARETSKI A
  • 专利权人:   UNIV CALIFORNIA
  • 国际专利分类:   C23C014/02, C23C014/04, C23C014/18, C23C014/30, C23C016/01, C23C016/02, C23C016/26, G01L001/18, G01N021/65, G01N027/02
  • 专利详细信息:   US2022091042-A1 24 Mar 2022 G01N-021/65 202235 English
  • 申请详细信息:   US2022091042-A1 US541764 03 Dec 2021
  • 优先权号:   US238489P, US541764

▎ 摘  要

NOVELTY - System comprises: a chamber; a composite film structure on which a biological sample is disposed, the composite film structure comprising a metallic layer in contact with a graphene layer, and a polymer layer in contact with either the metallic layer or the graphene layer; electrical connections for electrically accessing the composite film structure; and a central opening in the chamber, the central opening configured to receive the biological sample disposed on the composite film structure, where the biological sample comprises cultured cells or tissues, and the metallic layer comprises metallic nanoislands. The metallic nanoislands comprise a plasmonically active metal comprising copper, silver, palladium, gold or platinum nanoislands. USE - The system is useful for: measuring mechanical movements in a biological sample (claimed); and healthcare, wellness, haptic technology and instrumented prostheses. ADVANTAGE - The system can be the ease of tracking and analyzing the metallic nanoislands. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for measuring mechanical movements in the biological sample.