• 专利标题:   Composition used to isolate extracellular vesicle, comprises many magnetic particles, each magnetic particle comprising core particle and targeting moiety extending from the core particle via photocleavable linker.
  • 专利号:   US2022073999-A1
  • 发明人:   HE M
  • 专利权人:   UNIV KANSAS STATE RES FOUND, UNIV KANSAS
  • 国际专利分类:   A61K047/69, A61K049/00, B01L003/00, B03C001/015, B03C001/30, C12Q001/6886, G01N033/543, G01N033/574
  • 专利详细信息:   US2022073999-A1 10 Mar 2022 C12Q-001/6886 202247 English
  • 申请详细信息:   US2022073999-A1 US514724 29 Oct 2021
  • 优先权号:   US748470P, US514724

▎ 摘  要

NOVELTY - Composition comprises many magnetic particles, each magnetic particle comprising a core particle and a targeting moiety extending from the core particle via a photocleavable linker, the photocleavable linker connecting the magnetic particle and the targeting moiety, where the targeting moiety specifically binds to an extracellular vesicle surface marker for isolating the extracellular vesicle. USE - The composition is useful for isolating an extracellular vesicle, where the extracellular vesicle is an exosome (claimed) and the vesicle is useful as cancer vaccines, immunotherapy delivery, and other delivery associated with in vivo transportation. Test details are described but no results given.