▎ 摘　　要

NOVELTY - Implanting artificial structure into bone of patient comprises (a) obtaining mesenchymal stem cells and stem cell precursors, including quiescent mesenchymal stem cells, (b) obtaining a bone orphogenic protein, (c) obtaining an osteoprotegerin, (d) obtaining a platelet rich plasma, (e) obtaining a platelet poor plasma, (f) forming fibrin clot from platelet poor plasma, (g) combining fibrin clot, mesenchymal stem cells and stem cell precursors, bone morphogenic protein, osteoprotegerin, and platelet rich plasma to form an implant solution, (h) providing surgically created receptor site in bone, (i) providing an artificial implant structure, (j) imbibing artificial implant structure in implant solution, and (k) inserting artificial implant structure into receptor site. USE - The method is useful for implanting artificial structure into bone of patient. ADVANTAGE - The method: improves cellular functions in vitro and in vivo applications of dental implants; and does not cause side effects. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for: (1) implanting an artificial implant structure into an implant site in a bone of a patient, comprising (a) drawing a sample of whole blood from patient, (b) dividing sample into first and second portions and recovering Platelet Rich Protein (PRP) from first portion, (c) removing all cellular components from second portion, (d) forming fibrin clot from second portion, (e) obtaining from patient a sample of mesenchymal stem cells and their precursors, including quiescent mesenchymal stem cells, (f) combining mesenchymal stem cells and their precursors, with BMP-2, PRP, and osteoprotegerin and with fibrin clot to form an implant solution, (g) applying implant solution to an artificial implant structure, (h) incubating artificial implant structure in implant solution for a time period, (i) irrigating implant site with implant solution, and (j) installing artificial implant structure into irrigated implant site; (2) implant solution for implanting artificial implant devices into bones, comprising mature stem cells, mesenchymal stem cells, fibrin, bone morphogenic protein, osteoprotegerin, and platelet rich plasma; and (3) implanting artificial implant device in bone, comprising (i) forming an implant solution including mature stem cells, mesenchymal stem cells, fibrin, a bone morphogenic protein, an osteoprotegerin, and a platelet rich plasma, (ii) coating artificial implant device with implant solution, (iii) preparing a surgical site for receiving artificial implant device, and (iv) installing coated artificial implant device into surgical site.