• 专利标题:   Kit useful for detecting pancreatic cancer prognosis conditioncomprises upstream and downstream primer sequences of miRNA.
  • 专利号:   CN114438217-A
  • 发明人:   LIU Y, LI X, GONG X
  • 专利权人:   UNIV SHENZHEN GEN HOSPITAL
  • 国际专利分类:   C12N015/11, C12Q001/686, C12Q001/6886, G16B025/10
  • 专利详细信息:   CN114438217-A 06 May 2022 C12Q-001/6886 202252 Chinese
  • 申请详细信息:   CN114438217-A CN10289507 23 Mar 2022
  • 优先权号:   CN10289507

▎ 摘  要

NOVELTY - Kit comprises upstream and downstream primer sequences of miRNA. The upstream and downstream primer sequences and auxiliary components of U6, miRNA comprises miRNA934, miRNA4444-2, miRNA3655, miRNA1301 molecules, the miRNAs in isolated samples of pancreatic cancer patients treated with the kit and prognosis to obtain the expression of the miRNA combination in the sample, The prognosis of patients with pancreatic cancer was determined according to the high and low expression components. USE - The kit is useful for detecting pancreatic cancer prognosis condition. ADVANTAGE - The invention detects the expression condition of 4 miRNAs specifically expressed in the patient sample, and establishes a diagnosis reagent box distinguishing patient cancer prognosis bad, which can comprehensively improve the pancreatic cancer prognosis curative effect and metastasis, and the accuracy of recurrence prediction.