▎ 摘　　要

NOVELTY - Aptamer specific to coagulation factor XIII (FXIII) comprises polynucleotide sequence having 90% identity to 19 nucleotides (SEQ ID NO: 1), given in the specification. USE - Aptamer specific to coagulation factor XIII (FXIII) used for treating disease associated with thrombosis such as venous thrombosis such as branch retinal vein occlusion, Budd-Chiari syndrome, cavernous sinus thrombosis, central retinal vein occlusion, cerebral venous sinus thrombosis, deep vein thrombosis, jugular vein thrombosis or arterial thrombosis such as hepatic artery thrombosis, limb ischemia, myocardial infarction or stroke (all claimed). ADVANTAGE - The aptamer specific to coagulation factor XIII (FXIII) has greater chemical reactivity. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for treating disease associated with thrombosis, which involves: a. administering to subject effective amount of aptamer.