• 专利标题:   Preparing carbon-based nanocomposite material useful for preparing targeted tumor medicine, comprises e.g. grinding carbon-based nanomaterial, ultrasonically processing, adding isopropanol, centrifuging, removing supernatant and dispersing.
  • 专利号:   CN113368250-A
  • 发明人:   ZHANG Y, LIN J, ZHUO Y, ZOU F, ZHONG W, WANG L, BAO W, LI Y, ZOU Z
  • 专利权人:   UNIV GUANGZHOU FIRST PEOPLES HOSPITAL
  • 国际专利分类:   A61K047/02, A61K041/00, A61K047/52, A61K033/24, A61K033/26, A61K033/34, A61P035/00, B82Y005/00, B82Y020/00, B82Y030/00, B82Y040/00, C01B032/15
  • 专利详细信息:   CN113368250-A 10 Sep 2021 A61K-047/02 202181 Pages: 11 Chinese
  • 申请详细信息:   CN113368250-A CN10556254 20 May 2021
  • 优先权号:   CN10556254

▎ 摘  要

NOVELTY - Preparing carbon-based nanocomposite material comprises (i) grinding carbon-based nanomaterial, dispersing in ethanol, ultrasonically processing in probe water bath, centrifuging, cleaning, and taking suspension I to obtain carbon-based nanoparticle solution; (ii) centrifuging carbon-based nano-particle solution, removing supernatant and drying to obtain reactant A, adding isopropanol into reactant A to obtain suspension II, and mixing suspension II and metal ion solution to obtain suspension III, where the volume ratio of the suspension II and the metal ion solution is 1:0.01-1:100; and (iii) centrifuging suspension III, removing supernatant to obtain reactant B, cleaning, and dispersing. USE - The material is useful for preparing targeted tumor medicine. ADVANTAGE - The material has more residence time in tumor of free ions; and plays role of chemodynamic therapy. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for carbon-based nanocomposite material, prepared as mentioned above.