• 专利标题:   Method for adjusting light ion gating efficiently based on interaction between graphene lid and bionic DNA, comprises switching cis and trans states of Azo-DNA through changes in light, and controlling ion gating controlled reversibly.
  • 专利号:   CN111307721-A
  • 发明人:   LI G, SHI L, JIA F, WANG L, CHAI W, DUAN C
  • 专利权人:   UNIV NANJING
  • 国际专利分类:   G01N021/19, G01N021/25
  • 专利详细信息:   CN111307721-A 19 Jun 2020 G01N-021/19 202057 Pages: 13 Chinese
  • 申请详细信息:   CN111307721-A CN11514485 12 Dec 2018
  • 优先权号:   CN11514485

▎ 摘  要

NOVELTY - Adjusting light ion gating efficiently based on interaction between graphene lid and bionic deoxyribonucleic acid (DNA) comprises switching cis and trans states of Azobenzene (Azo)-DNA through changes in light, controlling ion gating controlled reversibly, after modification on a barrier layer of the nano-meter channel-ion channel complex, exhibiting single-stranded state under ultraviolet irradiation by Azo-DNA, binding single-stranded Azo-DNA tightly using gene ontology (GO) tightly, where the nano-meter structure system is in a closed state, after being irradiated with visible light, due to Azo's light responsiveness, Azo-DNA becomes a hairpin structure, and binding double-stranded DNA with GO stably, so it switches to the open state. USE - Method for adjusting light ion gating efficiently based on interaction between graphene lid and bionic DNA. ADVANTAGE - The method has good bio-compatibility and diversified design with potential applications in nano-medicine, biosensors and controlled drug delivery.