▎ 摘　　要

NOVELTY - Preparing graphene oxide-based composite nanofiber tissue engineering scaffold comprises (i) dissolving the silk fibroin and the macromolecule polymer in a solvent and stirring until completely dissolving to obtain spinning solution, (ii) subjecting spinning solution to electrospinning to obtain nanofiber membrane, fumigating by ethanol or its solution and drying to obtain silk fibroin/polymer composite nanofiber scaffold material, (iii) immersing silk fibroin/polymer composite nanofiber scaffold material in oxidized graphene dispersion, removing and drying to obtain final product. USE - The composite nanofiber tissue engineering scaffold is useful in blood vessels, nerve catheters, bone tissue, tendon tissue and skin(claimed). ADVANTAGE - The composite nanofiber tissue engineering scaffold has high mechanical properties and provides biological signals for tissue growth, promotes the cell adhesion, proliferation and differentiation. DETAILED DESCRIPTION - Preparing graphene oxide-based composite nanofiber tissue engineering scaffold comprises (i) dissolving the silk fibroin and the macromolecule polymer in a solvent and stirring until completely dissolving to obtain spinning solution, (ii) subjecting the spinning solution obtained in step (i) to electrospinning to obtain nanofiber membrane, fumigating by ethanol or its solution and drying to obtain silk fibroin/polymer composite nanofiber scaffold material, (iii) immersing silk fibroin/polymer composite nanofiber scaffold material obtained in step (ii) in graphene oxide dispersion, removing and drying to obtain final product.