▎ 摘　　要

NOVELTY - Preparing multiple polydopamine ibuprofen imprinted nanocomposite membrane comprises (1) mixing tetraethyl orthosilicate and ethanol to obtain first solution, mixing ammonia, ethanol and distilled water to obtain second solution, and vacuum drying to obtain final product silicon dioxide nanoparticles, (2) dissolving tris(hydroxymethyl)aminomethane hydrochloride and dopamine hydrochloride in deionized water to obtain mixed solution, (3) adding polyvinylidene fluoride powder, polyvinylpyrrolidone and polydopamine-based imprinted silicon dioxide/activated carbon ball to methylpyrrolidone, and scraping resulting final solution on glass grinding tool, (4) dissolving tris(hydroxymethyl)aminomethane hydrochloride and dopamine hydrochloride in deionized water to obtain mixed solution, (5) adding titanium dioxide (TiO2), graphene oxide (GO) and ibuprofen to above mixed solution, and (6) eluting obtained membrane sample with eluent to remove template molecules and unreacted monomers. USE - The nanocomposite membrane is useful for selective adsorption and separation of ibuprofen in mixed solution containing ibuprofen (claimed). ADVANTAGE - The method solves the shortcomings of the existing ibuprofen molecularly imprinted polymer that are difficult to recycle and easy to produce secondary pollution. DETAILED DESCRIPTION - Preparing multiple polydopamine ibuprofen imprinted nanocomposite membrane comprises (1) mixing tetraethyl orthosilicate and ethanol to obtain first solution, mixing ammonia, ethanol and distilled water to obtain second solution, adding first solution to second solution and mixing, adding ethanol and deionized water for centrifugal cleaning while stirring for period of time to obtain mixed solution, collecting the solid product after centrifugation, and vacuum drying to obtain the final product silicon dioxide nanoparticles, (2) dissolving tris(hydroxymethyl)aminomethane hydrochloride and dopamine hydrochloride in deionized water to obtain mixed solution, adjusting the pH value of the mixed solution, adding the silicon dioxide nanoparticles, activated carbon balls and ibuprofen prepared in the step (1) to the above mixed solution, stirring and reacting for period of time at room temperature, and obtaining the polydopamine-based imprinted silicon dioxide/activated carbon ball after washing and drying, (3) adding polyvinylidene fluoride powder, polyvinylpyrrolidone and the polydopamine-based imprinted silicon dioxide/activated carbon ball prepared in the step (2) to methylpyrrolidone, obtaining mixed solution after fully stirring and dispersing, continuously stirring for period of time at certain temperature after defoaming and sealing, scraping the resulting final solution on the glass grinding tool with doctor blade, soaking in deionized water for the phase inversion process after the stirring, washing the final membrane material with water many times, obtaining the silicon dioxide/activated carbon ball nanocomposite imprinted film, and cutting it into specific size film, (4) dissolving tris(hydroxymethyl)aminomethane hydrochloride and dopamine hydrochloride in deionized water to obtain mixed solution, adjusting the pH value of the mixed solution, soaking the silicon dioxide/activated carbon ball nanocomposite imprinting membrane prepared in the step (3) into the above mixed solution, oscillating for period of time at room temperature, and obtaining the polydopamine modified silicon dioxide/activated carbon ball nanocomposite double-layer imprinted film after washing and drying, (5) dissolving tris(hydroxymethyl)aminomethane hydrochloride and dopamine hydrochloride in deionized water to obtain mixed solution, adjusting the pH value of the mixed solution, adding titanium dioxide (TiO2), graphene oxide (GO) and ibuprofen to the above mixed solution, stirring and reacting for period of time at room temperature, and washing and drying to obtain polydopamine-based imprinted TiO2/GO, and (6) diluting the polydopamine-based imprinted TiO2/GO with deionized water to certain concentration, vacuum filtering the diluent on the surface of the polydopamine modified silicon dioxide/activated carbon sphere nanocomposite double-layer imprinted membrane prepared by the step (4), after ultrasonic treatment of the diluted solution for period of time, obtaining the final product after drying, eluting the obtained membrane sample with eluent to remove template molecules and unreacted monomers, washing with methanol, and vacuum drying to obtain multiple polydopamine ibuprofen imprinted nanocomposite membranes.