▎ 摘　　要

NOVELTY - The method comprises (i) oxidizing and cutting carbon fiber by nitric acid sulfuric acid to synthesize watersoluble graphene quantum dots; (ii) using dipalmitoyl phosphatidylcholine, soybean hydrogenated phospholipid, distearic phosphatidyl ethanolamine-polyethylene glycol 2000 as raw material, using modified reverse evaporation method to synthesize liposome, adding graphene quantum dot solution into the process of synthesizing liposome, forming the graphene quantum dot solution by dissolving graphene quantum dot prepared between the phosphate buffer solution with low ion concentration, passively and efficiently loading the graphene quantum dot into the hydrophilic core of the liposome and filtering the suspension by film to obtain the suspension containing liposome loading graphene quantum dot with uniform particle size; and (iii) using the glucan gel column chromatography to separate the liposome loaded graphene quantum dots in the suspension and the free graphene quantum dots. USE - The method is useful for efficient loading graphene quantum dot with liposome. ADVANTAGE - The method efficiently encapsulates the graphene quantum dot into the hydrophilic core of the liposome, which can effectively avoid the graphene quantum dot being quickly removed and degraded by the kidney because of too small size, prolongs the circulation time in the graphene quantum dot body, and improves the graphene quantum dot biomedical application. DETAILED DESCRIPTION - The method comprises (i) oxidizing and cutting carbon fiber by nitric acid sulfuric acid to synthesize watersoluble graphene quantum dots; (ii) using dipalmitoyl phosphatidylcholine, soybean hydrogenated phospholipid, distearic phosphatidyl ethanolamine-polyethylene glycol 2000 as raw material, using modified reverse evaporation method to synthesize liposome, adding graphene quantum dot solution with concentration of 12.5 mg/ml into the process of synthesizing liposome, forming the graphene quantum dot solution by dissolving graphene quantum dot prepared between the a in phosphate buffer solution with low ion concentration, passively and efficiently loading the graphene quantum dot into the hydrophilic core of the liposome, using the liposome squeezer, filtering the suspension through polycarbonate film to obtain the suspension containing liposome loading graphene quantum dot with uniform particle size, where the liposome load graphene quantum dot to form graphene quantum dots-liposomes composite structure of nano material; and (iii) using the glucan gel column chromatography to separate the liposome loaded graphene quantum dots in the suspension and the free graphene quantum dots. An INDEPENDENT CLAIM is also included for a liposome-loaded graphene quantum dot composite material.