▎ 摘　　要

NOVELTY - Sensor comprises a substrate, a first electrode layer and a second electrode layer formed on the substrate and having a set of fingers spaced apart from each other by a predetermined width and spacing and a comb-tooth electrode (108) formed on a substrate. The set of fingers provided on the first and second electrodes are spaced apart in a mutually interlocking pattern. An impedance measuring circuit is electrically connected to the comb-shaped electrode. Each of the set of fingers has a wavy shape so as not to have a straight electrode edge. The wave shape has a periodic pattern. The wavelength is 5-1000 mu m and the wave height is in the range of 2-1000 mu m. USE - Comb-toothed electrode-based capacitance sensor for monitoring growth of microorganisms, such as E.coli, Salmonella choleraesuis, Salmonella bongori, Salmonella typhimurium, Listeria monocytogenes, Listeria denitrificans, Listeria grayi, Listeria murrayi, S.enteritidis, Y. enterocolitica, S. aureus, B. cereus, and L. monocytognes (all claimed). ADVANTAGE - The high sensing sensitivity can be obtained by measuring the capacitance change according to the adhesion of microorganisms or cells in the sample in contact with the sensor. The growth of cells can be monitored in real time without a label. The measurement capability for a small amount of sample can be secured. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for monitoring the growth and/or drug response of microorganisms or bacteria using a capacitance sensor, which involves providing a sample to be analyzed; and measuring a change in capacitance by contacting a capacitance sensor with the solution containing the sample. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic representation of a microbial growth and/or drug response monitoring system using a capacitance sensor. Stopper (103) Sample extraction port (104) Filter (105) Wires (106) Filler (107) Electrode (108)