▎ 摘　　要

NOVELTY - The material has a cobalt-containing compound used as precursor of cobalt. A carbon-nano-material is used as a substrate and synthesized by chemical bonding action, where the chemical bonding action comprises interaction, amide bond cross-linking or covalent bonding, and the carbon nano-material is carbon nano-tube and graphene carbon nano-tube, and mass ratio of the cobalt-containing compound to the carbon nano-material is 1:5-20. USE - Single-atom cobalt nano-enzyme material for use in a biological electrode of a flexible electrochemical chip sensor (all claimed) in vivo and in vitro biological research and clinical diagnosis. ADVANTAGE - The material has wide linear range, low detection limit, fast and sensitive response, good reproducibility, stability and selectivity, and can achieve sensitive detection of in vivo and in vitro NO. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a flexible electrochemical chip sensor. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic diagram of a flexible electrochemical chip sensor printing and mouse and living cell sensing.