• 专利标题:   Preparing nanorod array coating of graphene oxide in implant material and bone tissue, involves performing micro-arc oxidation treatment on titanium or titanium alloy in an electrolyte containing calcium acetate, beta-sodium glycerophosphate and sodium hydroxide.
  • 专利号:   CN114504678-A, CN114504678-B
  • 发明人:   XUE Z, HAN Y
  • 专利权人:   UNIV XIAN JIAOTONG
  • 国际专利分类:   A61L027/06, A61L027/30, A61L027/32, A61L027/50, C23C018/12, C25D011/26
  • 专利详细信息:   CN114504678-A 17 May 2022 A61L-027/06 202270 Chinese
  • 申请详细信息:   CN114504678-A CN10152402 18 Feb 2022
  • 优先权号:   CN10152402

▎ 摘  要

NOVELTY - Preparing nanorod array coating of graphene oxide involves performing micro-arc oxidation treatment on titanium or titanium alloy in an electrolyte containing calcium acetate, beta-sodium glycerophosphate and sodium hydroxide to obtain amorphous titanium coating containing calcium and phosphors. The amorphous titanium oxide coating containing calcium and phosphorus is first immersed in sodium hydroxide solution with a concentration of 0.01-0.025M for hydrothermal reaction, then the obtained coating is placed in a mixed solution of calcium disodium ethylenediaminetetraacetate, beta-sodium glycerophosphate and sodium hydroxide, hydrothermal treatment at 100-140degrees Celsius to obtain a nanorod arrayed coating containing hydroxyapatite. USE - Method for preparing nanorod array coating of graphene oxide used in implant material and bone tissue (claimed). ADVANTAGE - The method has high repeatability and provides excellent anti-bacterial effect, in simple and controllable manner. DETAILED DESCRIPTION - Preparing nanorod array coating of graphene oxide involves performing micro-arc oxidation treatment on titanium or titanium alloy in an electrolyte containing calcium acetate, beta-sodium glycerophosphate and sodium hydroxide to obtain amorphous titanium coating containing calcium and phosphors. The amorphous titanium oxide coating containing calcium and phosphorus is first immersed in sodium hydroxide solution with a concentration of 0.01-0.025M for hydrothermal reaction, then the obtained coating is placed in a mixed solution of calcium disodium ethylenediaminetetraacetate, beta-sodium glycerophosphate and sodium hydroxide, hydrothermal treatment at 100-140degrees Celsius to obtain a nanorod arrayed coating containing hydroxyapatite, immersed the nanorod arrayed coating of hydroxyapatite in a mixed system of calcium disodium ethylenediaminetetraacetate, beta-sodium glycerophosphate, sodium hydroxide and graphene oxide, and graphene oxide and the mixed solution. The hydrothermal treatment is performed at 110-140degrees Celsius to obtain product.