• 专利标题:   Immune electrochemical sensor useful for detecting beta-adrenergic receptor agonists, comprises glassy carbon electrode substrate, graphene/chitosan film and a detection layer (4-(4-(2-tert-butylamino-1-hydroxyethyl)phenyl)butanoic acid).
  • 专利号:   CN106645699-A, CN106645699-B
  • 发明人:   SHAO K, HUANG A, ZHAO B, WU J
  • 专利权人:   UNIV NANJING NORMAL, UNIV NANJING NORMAL
  • 国际专利分类:   G01N027/30, G01N027/327, G01N033/543
  • 专利详细信息:   CN106645699-A 10 May 2017 G01N-033/543 201740 Pages: 15 Chinese
  • 申请详细信息:   CN106645699-A CN11164480 16 Dec 2016
  • 优先权号:   CN11164480

▎ 摘  要

NOVELTY - Immune electrochemical sensor comprises a glassy carbon electrode substrate, a graphene/chitosan mixed film coated on surface of the glassy carbon electrode substrate, and a detection layer, where material of the detection layer is solution of beta-agonist universal hapten 4-(4-(2-tert-butylamino-1-hydroxyethyl)phenyl)butanoic acid (I). USE - The immune electrochemical sensor is useful for detecting seven kinds of beta-adrenergic receptor agonists including clenbuterol, salbutamol, mabuterol, brombuterol, cimbuterol, tulobuterol and terbutaline in foodstuffs (claimed). DETAILED DESCRIPTION - Immune electrochemical sensor comprises a glassy carbon electrode substrate, a graphene/chitosan mixed film coated on surface of the glassy carbon electrode substrate, and a detection layer, where material of the detection layer is solution of beta-agonist universal hapten 4-(4-(2-tert-butylamino-1-hydroxyethyl)phenyl)butanoic acid of formula (I). An INDEPENDENT CLAIM is also included for preparation of the immune electrochemical sensor, comprising coating graphene/chitosan dispersion on the surface of the clean glassy carbon electrode substrate, and drying to form a film, then spraying solution of (I) on surface of the film, and drying to obtain sensor.