▎ 摘　　要

NOVELTY - Preparing sulfadimethoxine molecularly imprinted electrochemical sensor involves performing electropolymerization to form a molecularly imprinted polymer in a phosphate buffer solution of methylene blue and sulfadimethoxine. The molecularly imprinted electrochemical sensor prepared by this method has a detection limit of 2.8x 10-7 mol/L for sulfadimethoxine, and a linear range of 6x 10-7mol/Lx 10-6 mol/L. The glassy carbon electrode is polished with 0.5 micrometer aluminum oxide (Al2O3) powder on the suede, and performed ultrasonic washing in ethanol and deionized water for various minutes, and then scanned the electrode in potassium ferricyanide (K3Fe(CN)6) to obtain a reversible cyclic voltammetry peak (peak current ratio of 1:1, peak potential difference less than 70 millivolts), which proves the electrode treatment it is good. The dispersed graphene suspension is dropped onto the glassy carbon electrode to form a uniform dispersion layer. USE - Method for preparing sulfadimethoxine molecularly imprinted electrochemical sensor for graphene-modified glassy carbon electrode. ADVANTAGE - The method enables to prepared sulfadimethoxine molecularly imprinted electrochemical sensor, that has good stability and selectivity, and the preparation method is simple and practical. DETAILED DESCRIPTION - Preparing sulfadimethoxine molecularly imprinted electrochemical sensor involves performing electropolymerization to form a molecularly imprinted polymer in a phosphate buffer solution of methylene blue and sulfadimethoxine. The molecularly imprinted electrochemical sensor prepared by this method has a detection limit of 2.8x 10-7 mol/L for sulfadimethoxine, and a linear range of 6x 10-7mol/Lx 10-6 mol/L. The glassy carbon electrode is polished with 0.5 micrometer aluminum oxide (Al2O3) powder on the suede, and performed ultrasonic washing in ethanol and deionized water for various minutes, and then scanned the electrode in potassium ferricyanide (K3Fe(CN)6) to obtain a reversible cyclic voltammetry peak (peak current ratio of 1:1, peak potential difference less than 70 millivolts), which proves the electrode treatment it is good. The dispersed graphene suspension is dropped onto the glassy carbon electrode to form a uniform dispersion layer, which is dried naturally to obtain a graphene-modified electrode. The methylene blue and sulfadimethoxine are dissolved in a phosphate buffer solution and mix them uniformly. The molar ratio of methylene blue and sulfadimethoxine is 1:1-6:1. The previously mixed solution is used as an electrolyte solution, placed the graphene-modified electrode in the mixed solution, and performed electrochemical polymerization using cyclic voltammetry to form a molecularly imprinted polymer. The sulfadimethoxine template molecule is washed away with ethanol/acetic acid solution to obtain a molecularly imprinted electrochemical sensor of sulfadimethoxine.