• 专利标题:   Microcapsule useful in preparation of drug-loaded/chitosan microcapsules, prepared by introducing graphene into chitosan microcapsule membrane wall, thus forming spherical graphene/chitosan microcapsule.
  • 专利号:   CN104688714-A, CN104688714-B
  • 发明人:   CHEN H, CHEN Y, HE S, WANG H, ZHANG K, XIA Y, XUE W, ZHAO Z
  • 专利权人:   UNIV WUHAN TECHNOLOGY
  • 国际专利分类:   A61K047/04, A61K047/36, A61K009/50
  • 专利详细信息:   CN104688714-A 10 Jun 2015 A61K-009/50 201565 Pages: 10 Chinese
  • 申请详细信息:   CN104688714-A CN10124373 20 Mar 2015
  • 优先权号:   CN10124373

▎ 摘  要

NOVELTY - Microcapsule is prepared by introducing graphene into chitosan microcapsule membrane wall, thus forming spherical graphene/chitosan microcapsule, where the microcapsule has size of 300-1000 mu m and particle size distribution coefficient of less than 6%. USE - The microcapsule is useful in preparation of drug-loaded/chitosan microcapsules (all claimed). ADVANTAGE - The microcapsule is prepared simply with high reproduction quality. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for method for preparing the microcapsule, which involves dispersing first quaternary chitosan modified graphene, forming chitosan solution, preparing graphene/chitosan mixed droplets, adding anionic surfactant, quaternary chitosan and modified chitosan graphene molecules to the mixture, introducing the mixture into microcapsule membrane wall, and forming graphene/chitosan microcapsules.