▎ 摘　　要

NOVELTY - Graphene/silicon biosensor comprise multiple silicon nanostructure (120) aligned and bonded to substrate (110) and coated with functional material including 3-aminopropyltriethoxysilane (3-APTES) or glutaraldehyde. The graphene layer (130) is disposed on the silicon nanostructure. The electrode (140a, 140b) is formed on lower portion of the substrate and upper portion of the graphene layer, respectively. USE - Graphene/silicon biosensor used in DNA detecting apparatus (claimed). ADVANTAGE - The graphen/silicone biosensor has capability of detecting DNA with high binding density. DETAILED DESCRIPTION - Graphene/silicon biosensor comprise multiple silicon nanostructure aligned and bonded to substrate and coated with functional material including 3-aminopropyltriethoxysilane (3-APTES) or glutaraldehyde. The graphene layer is disposed on the silicon nanostructure. The electrode is formed on lower portion of the substrate and upper portion of the graphene layer, respectively. The current variation of DNA is detected according to target DNA that is pair of target DNAs which are attached to a predetermined probe DNA adhered to surface of silicon nanostructure through functional material. The surface of silicon nanostructure forms covalent bond and comprises 3-aminopropyltriethoxysilane containing amino group. The graphene/silicon biosensor that binds to glutaraldehyde is a chemical modification agent of protein that reacts with an amino group (-NH2) and bridges it by enhancing binding force with probe DNA, where graphene/silicon biosensor distinguishes substrate. An INDEPENDENT CLAIM is included for a DNA detecting apparatus, which comprises graphene/silicon biosensor, and detection unit for detecting change of current amount depending on presence or absence of a pair of target DNA attached to predetermined probe DNA attached to surface of silicon nanostructure through functional material. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic view of graphen/silicone biosensor used in DNA detecting apparatus (claimed). Substrate (110) Silicon nanostructure (120) Graphene layer (130) Electrode (140a, 140b)