• 专利标题:   Graphene sensor for rapid detection of Gram-negative bacteria lipopolysaccharide, has closed sample cell side wall fixed in middle of graphene layer, where tip of wall is sealed with opening of sample cell, to constitute sample package.
  • 专利号:   CN106290541-A
  • 发明人:   TANG C, HUANG Y, LIANG H, LI S
  • 专利权人:   TIANJIN XINUO BIOLOGICAL PHARM CO LTD
  • 国际专利分类:   G01N027/48
  • 专利详细信息:   CN106290541-A 04 Jan 2017 G01N-027/48 201726 Pages: 7 Chinese
  • 申请详细信息:   CN106290541-A CN10632404 03 Aug 2016
  • 优先权号:   CN10632404

▎ 摘  要

NOVELTY - The sensor has sample cell opening formed in upper surface of housing. A back gate electrode (6) is arranged on lower surface of insulating substrate (5). An antibody-modified graphene layer (4) is formed on top surface of substrate. A source (7) and a drain (3) are formed on left and right sides of graphene layer. A closed sample cell side wall (2) is fixed in the middle of the graphene layer. The tip of sample cell wall is sealed with the opening of sample cell on the shell (1), to constitute a package of samples. USE - Graphene sensor is useful for rapid detection of Gram-negative bacterial lipopolysaccharide. ADVANTAGE - The preparation method can realize stable, batch and low cost preparation of graphene-based biosensor, which promotes the high efficiency and precision of biological detection. DETAILED DESCRIPTION - The antibody is modified by specifically binding factor C in limulus amebocyte lysate to Gram-negative bacterial endotoxin. An INDEPENDENT CLAIM is included for a preparation method of graphene sensor. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic view of the graphene sensor. Shell (1) Sample cell side wall (2) Drain (3) Graphene layer (4) Insulating substrate (5) Back gate electrode (6) Source (7)